2025 Trastevere itinerary

Rome is a city of timeless, everlasting charm, capable of captivating both visitors from all over the world and those who call it home. Among its many districts, Trastevere is one of the most beloved and distinctive: here, time seems to stand still, and wandering its narrow alleyways is all it takes to immerse yourself in the most romantic and bohemian side of Roman life. 

Trastevere is a district that never ceases to surprise, where local authenticity and international tourism meet in harmony. This is why it is considered the heart of Rome – celebrated by poets, directors and musicians as a place with its own unique spirit within a vast city where it's easy to get lost. If you want to discover what to see in this district, we've prepared the perfect guide for you: a Trastevere itinerary featuring must-see highlights, hidden gems, and even a prestigious hotel that reflects the soul of the neighbourhood.

What to see in Trastevere in one day

Trastevere's charm stems from its long history, rooted in the imperial past of the Capital, to which it became officially annexed in the 3rd century AD. Today, with its ivy-covered buildings, small artisan workshops and taverns open late into the night, this is where you can truly savour the spirit of Rome – warm, welcoming and full of life. Here's what you absolutely can't miss on your Trastevere itinerary: 

• Ponte Sisto, connecting the district to the historic centre and offering a pleasant walk away from traffic.

• Tiber Island, a place suspended in time. Linked by two ancient bridges, this tiny island is home to the Fatebenefratelli Hospital and the Church of San Bartolomeo all'Isola.

• Piazza Trilussa, the beating heart of Trastevere's nightlife. Dedicated to the Roman poet Carlo Alberto Salustri, known as Trilussa, this square is a gathering point for street performers, young people and tourists.

• Villa Farnesina, one of Rome's most elegant Renaissance residences, built for the banker Agostino Chigi. Inside you'll find frescoes by Raphael, Sebastiano del Piombo and Peruzzi, as well as a stunning garden. Also worth highlighting is its beautiful garden.

• Basilica of Santa Maria in Trastevere, the artistic heart of the district and the most famous of Trastevere's monuments. Its golden façade and the Byzantine mosaics in the apse make it truly unique, and the square in front is one of the central meeting points of Roman life.

• The Janiculum Hill (Gianicolo), Rome's balcony. One of the best panoramic viewpoints over the city, also home to the majestic Fontana dell'Acqua Paola.

• Porta Portese Market, famous throughout Rome and beyond. On Sundays, it becomes a true ritual: dive into the mix of colours, voices and aromas that evoke the Rome of the past. 

Hidden places in Trastevere: five special spots

To truly experience Trastevere, you must also explore the most unusual places and the little-known gems beyond the classic tourist trails. Among the must-see places, we suggest: 

• The Ancient Pharmacy of Santa Maria della Scala. Originally a "spezieria" (apothecary), the friars of the Discalced Carmelite convent once produced ointments and medicines here. It opened to the public in the late 17th century, becoming renowned and frequented by illustrious figures such as cardinals, princes and even popes. Today it is a museum open by appointment, where you can admire the original sales room with jars, bottles and equipment from the time. 

• The Botanical Garden, perfect for those seeking a quiet oasis in the centre of the city. Covering 12 hectares and home to 300 plant species, this green haven is divided into two areas: the upper part, the original woodland area of the park, and the lower part, featuring rose gardens, Japanese gardens and bamboo groves. 

• Arco San Callisto, whose distinctive vegetation makes it one of the district's most photographed corners.

• Tempietto del Bramante, considered the first Renaissance building in all of Rome. Located in the first courtyard of the Church of San Pietro in Montorio, this evocative Doric temple is free to visit. 

• Poster Art. Thanks to its multicultural soul, Trastevere has become the hub of Roman poster art and sticker art – illustrations created in workshops and then displayed on the walls of the district's alleyways. In the streets of Trastevere there are many, especially around Via della Lungaretta.

Where to stay in Rome in the Trastevere district

Your Trastevere itinerary wouldn't be complete without a hotel from which to explore the neighbourhood, and our recommendation is undoubtedly Trastevere Roma | UNA Esperienze.

The hotel, affiliated with Preferred Hotels & Resorts' prestigious Lifestyle Collection, has a soul deeply connected to the district. With a vibrant and captivating design that reflects the character of Trastevere, the property features a peaceful inner courtyard perfect for enjoying a cocktail, spacious rooms, and a guest relations service to support you throughout your stay. 

Where to eat in Trastevere

If you're wondering what or where to eat in Trastevere, the Vista Trastevere Roof Bar & Restaurant at the hotel offers a rich, carefully curated menu – perfect for those wanting to explore the best of Roman cuisine and the flavours of the neighbourhood. Alongside its delicious dishes, the restaurant will treat you to an extraordinary view over central Rome from its panoramic terrace.

Rome By Romans: experience authentic Trastevere 

Trastevere Roma | UNA Esperienze's latest innovation is called "Rome by Romans – Trastevere": an immersive project that, starting in 2026, will allow guests to enjoy unique sensory experiences within the district. 

Through encounters with local artists and artisans, guests will have the chance to discover and experience the true spirit of Trastevere, its history, and what makes it so special. In this way, the hotel becomes a key protagonist of the neighbourhood, enabling visitors to experience it from a completely new perspective.

Trastevere is not just one of Rome's districts – it is the beating heart of the city and guardian of its most authentic traditions. Book a stay at Trastevere Roma | UNA Esperienze to experience this neighbourhood in all its nuances.